Ion-682884-cs2
WebRx (ION-682884) is a ligand-conjugated antisense drug designed for receptor-mediated uptake by hepatocytes, the primary source of circulating transthyretin (TTR). Enhanced delivery of the antisense pharmacophore is ex-pected to increase drug potency and … WebCoronary Obstruction: Safety and Effectiveness of the ShortCut Device The purpose of this study is to determine the safety and effectiveness of an investigational device called the ShortCut in individuals with a risk for coronary obstruction following a repeated …
Ion-682884-cs2
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Web29 mrt. 2024 · As the leader in RNA-targeted therapeutics for more than three decades, Ionis has focused every moment on advancing drug discovery, development, and providing hope for patients. Our broadly applicable, versatile, and rapidly advancing technology …
WebSatisfactory completion of Treatment Period and the End of Treatment Visit of the Index Study (ION-682884-CS2) OR diagnosis of ATTR-CM and satisfactory participation on ISIS 420915- CS101 study as judged by the Investigator and Sponsor. Investigator is willing … WebAn Open-Label Extension Study to Assess the Long-Term Safety of Eplontersen (ION-682884) in Patients With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM) Snapshot Phase. Phase 3; Lead Sponsor. Ionis Pharmaceuticals, Inc. Study Type. …
WebThe Cloud Security and Compliance Series (CS2) is strictly for government contractors and those in higher education research institutions looking to meet cybersecurity regulations, address security threats, and glean best practices for their cloud investments. Areas of focus for CS2 events include, but are not limited to. CMMC 2.0. NIST 800-171. WebION-682884-CS2: Zadavatel: Ionis Pharmaceuticals, Inc., 2855 Gazelle Court Carlsbad, CA 92010, United States of America: Indikační skupina: Kardio-vaskulární systém Diagnóza: amyloidová kardiomyopatie (ATTR CM) Zařazovaná populace: Dospělí (18 - 65 let) …
WebION-682884-CS2 Page 2 of 5 RECITALS: ODŮVODNĚNÍ: WHEREAS, the Parties executed Agreement to conduct a clinical study with the title “A Phase 3 Global, Double-Blind, Randomized, Placebo‑ Controlled Study to Evaluate the Efficacy and Safety of ION …
Web1 jul. 2024 · AKCEA-TTR-LRX (ION-682884) is an antisense oligonucleotide (ASO) that inhibits the production of TTR. It has a similar design and sequence as inotersen (the parent compound), ... ciplaton for pregnancyWebGrup de recerca: Malalties Cardiovasculars. Servei: Cardiologia. Investigador/a principal: Rodríguez Palomares, Jose Fernando. Malaltia: Malalties del sistema circulatori. Fase: Fase III. Estat reclutament: Reclutant voluntaris. Estudio multicéntrico, aleatorizado, doble … dialysis halloween bulletin boardWebION-682884-CS2: A Phase 3 Global, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of ION-682884 in Patients with Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM) RACE-IT: Rapid Acute Coronary Syndrome … dialysis hancock miWebION-682884-CS2 REBECCA HUNG 200239 Additional qualification in progress 1/30/2024 ION-682884-CS3 Amanda Peltier 200127 Completed, but training still pending 2/24/2024 MASTERS-2 Michael Froehler Awaiting IRB# 12/21/2024 Mentor-Athena … dialysis halifaxWeb21 feb. 2024 · Sponsor Protocol Number: ION-682884-CS2. About this study. To evaluate the effectiveness of AKCEA-TTR-LRx compared to placebo for 120 weeks in patients with ATTR-CM receiving available standard of care (SoC). ... (ION‑682884 or placebo). Males … ciplaton for weight gainWeb23 okt. 2024 · A Phase 3 Global, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of ION-682884 in Patients With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM) Actual Study Start Date : March 13, 2024: … CARDIO-TTRansform: A Study to Evaluate the Efficacy and Safety of Eplontersen … Login to ClinicalTrials.gov PRS. The ClinicalTrials.gov Protocol Registration … dialysis hallucinationsWeb20 sep. 2024 · Qualifications (All must apply): Healthy males and females; Age 18 to 65; Non-marijuana users; Have a Body Mass Index (BMI) between 18 and 34 kg/m² *Check your BMI here; Available for 1 screening visit, a 1-night stay, 11 outpatient visits, and 3 follow-up dialysis hammonton nj