WebPhorbiplatin 8 is excited into the singlet state, then the singlet excited phorbiplatin undergoes intersystem crossing into the triplet excited state. ... View in full-text Similar publications... WebPhorbiplatin can be activated by low-power red-light irradiation. “Essentially phorbiplatin is the first small-molecule platinum (IV) prodrug that can be activated by a red light,” he adds. A prodrug is one that the body metabolises after it enters the body and becomes an active pharmacological drug. Platinum-based anti-cancer drugs ...
Issue: Chem - Home: Cell Press
WebPhorbiplatin is a small-molecule platinum (IV) anti-cancer prodrug. Prodrug is a compound that will only be pharmacologically active after activation inside the body. WebUnder short-period irradiation with low intensity of red light, without the need of any external catalyst, phorbiplatin is reduced to oxaliplatin, a first-line clinical antineoplastic, as well as ... simple c++ program for banking system
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WebPhorbiplatin, a Highly Potent Pt(IV) Antitumor Prodrug That Can Be Controllably Activated by Red Light. Chem 2024-12 Journal article DOI: 10.1016/j.chempr.2024.08.021 Part of ISSN: 2451-9294 Show more detail. Source: Zhigang Wang A Cisplatin-Loaded Immunochemotherapeutic Nanohybrid Bearing Immune Checkpoint Inhibitors for … WebJan 6, 2024 · The compound, called phorbiplatin, offers hope for minimising the damage that “normal” cells undergo during treatment for a broad range of cancers, in particular for breast and ovarian cancers. “Essentially … WebPhorbiplatin is a small-molecule platinum (IV) anti-cancer prodrug. Prodrug is a compound that will only be pharmacologically active after activation inside the body. Phorbiplatin is shown to be ... raw earth wholesale