Tspan4 if
WebFeb 1, 2024 · Among the 33 family members, 14 Tetraspanin proteins can induce migrasome formation when over-expressed (Huang et al., 2024).A subset of these migrasome-promoting Tetraspanins, including Tspan4 and Tspan9, have a higher capacity for promoting migrasome formation (Huang et al., 2024; Jiao et al., 2024).By inspecting … WebThe fluorescence intensity of both TSPAN4-GFP and CD9-GFP at the membrane tube increased significantly with time, indicating that the proteins migrated to regions of higher membrane curvature (Figure 1C, S1A). Hence, membrane curvature can induce TSPAN4 and CD9 redistribution from the flat membrane of GPMV to the curved tubular
Tspan4 if
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WebBackground Information. TSPAN4 (also known as NAG2 or TM4SF7) is a membrane protein of the tetraspanin superfamily, which are characterized by the presence of four conserved transmembrane regions. Tetraspanins have been involved in diverse processes such as cell activation and proliferation, adhesion and motility, differentiation, and cancer. Tetraspanin-4 is a protein that in humans is encoded by the TSPAN4 gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic … See more TSPAN4 has been shown to interact with CD9, ITGA6, CD29, CD49c and CD81. See more • Berditchevski F (2002). "Complexes of tetraspanins with integrins: more than meets the eye". J. Cell Sci. 114 (Pt 23): 4143–51. doi:10.1242/jcs.114.23.4143. PMID See more
WebThey can occur almost anywhere in the body, however they most commonly occur in the head, neck, arms, legs, trunk, and abdomen. Undifferentiated pleomorphic sarcoma (UPS) – an aggressive type of soft tissue sarcoma. UPS most commonly occurs in the arms and legs, and sometimes in the abdomen. It has a high incidence of recurrence and metastasis. WebFeb 18, 2024 · Directed migration is an important behavior of cell motility, which can be characterized quantitatively by their velocity and persistence, describing the rate of migration and the continuity in directional migration, respectively (Petrie et al., 2009; Gail and Boone, 1970).In addition to external regulation, such as chemotaxis in response to soluble …
WebTSPAN4_ENST00000397408 - Explore an overview of TSPAN4_ENST00000397408, with a histogram displaying coding mutations, full tabulated details of all associated variants, tissue distribution and any drug resistance data. WebHuman diseases caused by Tspan4 mutations. The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER. Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes. Human diseases associated with …
WebTSPAN4. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas …
WebImmunohistochemical analysis of TSPAN4 in paraffin-embedded human liver tissue. Sample was probed with a TSPAN4 polyclonal antibody ( Product # PA5-69344) at a dilution of … sharepoint file name too long errorWebTSPAN4. Synonyms. NAG2, TM4SF7. Organism names. Organism. Homo sapiens (Human) Taxonomic identifier. 9606 NCBI. Taxonomic lineage. Eukaryota > Metazoa > Chordata > … pop bestindex :WebSummary of RNA expression and protein localization based on data generated within the Human Protein Atlas project. Main locationi. Main subcellular location (s) and reliability … sharepoint file idWebApr 13, 2024 · 四次跨膜蛋白成员是迁移体形成的关键调节因子(如：TSPAN4和TSPAN9)。迁移体的形成是富含四次跨膜蛋白的宏结构域的组装过程，该过程增强了迁移体膜的刚性和弯曲度，介导了迁移体的形成，被称之为膜增强模型（membrane stiffening model）(Huang等 … pop be playtimeWebGene view. The gene view histogram is a graphical view of mutations across TSPAN4. These mutations are displayed at the amino acid level across the full length of the gene by default. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to ... sharepoint file pathWebAug 1, 2024 · Tspan4-GFP-expressing L929 cells (a) or tspan4a-GFP mRNA-injected zebrafish gastrulas (b) were stained with anti-integrin β1 antibody and observed by confocal microscopy. Scale bars, 10 μm. c , d . pop berryWebFunctional Associations. TSPAN4 has 5,174 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 63 datasets. pop beth harmon